DEVELOPMENT OF THE TEACHING OF
PHYSIOLOGY
IN OHIO*
by C. I. REED
Professor of Physiology, University
of Illinois, Chicago Professional Colleges
In order to bring the subject into
perspective it is necessary to
go back to the year 1726, when the
first curricular representation of
physiology was accorded by the
University of Edinburgh in appoint-
ing Andrew Sinclair professor of the
institutes of medicine. As
applied later, this title very often
covered much more than the con-
ventional scope of physiology as a
study of function in the healthy
organism. Not infrequently a professor
of the institutes and a pro-
fessor of physiology served
simultaneously in the same institution.
The first recognition came in America,
not in the first medical
school, but in the second one, that
founded in King's College, now
Columbia University, in 1769 when Peter
Middleton was appointed
professor of physiology and pathology.
Of course, the physiology
of that day was something quite
different from what is so desig-
nated today. Nevertheless, this
gentleman was a highly trained,
capable physician. The title lapsed
with his death in 1780, but was
restored in 1806 when a radical
reorganization took place which
gave Benjamin De Witt the chair of the
institutes.
Caspar Wistar was made professor of the
institutes in the Uni-
versity of Pennsylvania in 1789, and in
1792 a reorganization placed
Benjamin Rush in that chair. In point
of chronology this is the
oldest continuously functioning
department of physiology in North
America, as there is direct continuity
through several generations to
the present department in that
university. There was a brief flurry
of original research in the first few
years of the nineteenth century,
but this was not sustained. In the
medical school founded in Harvard
College in 1782 no provision was made
for teaching physiology
for nearly sixty years when Oliver
Wendell Holmes became pro-
fessor of anatomy and physiology.
* This article was read before the
Committee on Medical History and Archives of
the Ohio State Archaeological and
Historical Society at its annual meeting, held at
the Ohio State Museum on April 28, 1951.
355
356
Ohio State Archaeological and Historical Quarterly
The history of physiology in Ohio began
in a rather stormy era
in Cincinnati when Daniel Drake
(1785-1852) returned to that
city after a year as professor of
materia medica in Transylvania
University at Lexington, Kentucky, and
together with a number of
associates began a course of lectures
in which he covered the subjects
of medical practice, physiology, and
diseases of women and children.
The following year, 1819, he obtained
legislative authority for the
organization of a medical school that
could grant degrees, and in
1820 the Medical College of Ohio was
opened. For some reason,
not now clear, Drake was forced out of
the combination in 1822.
No one succeeded him for two years.
Then Jedediah Cobb became
professor of anatomy and physiology.
Drake went again to Tran-
sylvania for a few years, but finally
returned to Cincinnati to engage
in practice. A brief tenure in
Jefferson Medical College at Phila-
delphia culminated in his final
determination to declare war on his
enemies in Cincinnati. In 1831 he
founded the Western Medical
and Physical Journal, the first issue of which carried an announce-
ment of the medical department of Miami
University with Drake
as professor of the institutes and
George McClellan, professor of
anatomy and physiology. Joseph N.
McDowell, nephew of Ephraim
McDowell, was listed as adjunct
professor of anatomy and
physiology.
The trustees of the Medical College of
Ohio accomplished a
compromise whereby two of Drake's
enemies were forced out, and
he was made professor of clinical
medicine. Peace reigned only a
short time, however, and now Drake
openly declared his intention
to destroy the Medical College of Ohio.
By 1835 the school had
become so weakened that he believed the
time was ripe. He then
formed the medical department of Cincinnati College
with McDowell
as professor of anatomy and Samuel D.
Gross, later a surgeon of
note, as professor of pathology,
physiology, and medical juris-
prudence.
There was intense rivalry between the
two schools for four years,
but despite the able faculty assembled,
Drake's "spite college"
closed. Drake and Gross went to the
Louisville Medical Instiute
and McDowell to St. Louis. Cobb also
had gone to Louisville in
1837. There is no very clear history of
physiology for several years.
The Teaching of Physiology in Ohio 357
After Cobb left, John T. Shotwell
(1807-1850), a younger cousin
of Drake, succeeded to his chair and
even accomplished his own
election to the deanship. He finally,
in 1850, gave up the fight to
keep the tottering Medical College of
Ohio going. His resignation
was followed after a short time by
death from cholera.
At that time the medical department of
Transylvania University
was on the decline, but the school in
Louisville was becoming a
formidable rival. Two cult schools had
opened in Cincinnati. Some-
thing had to be done. Public sentiment
demanded Drake's return.
His prestige had grown until he was the
most popular and in-
fluential medical personage in the
West. He was recalled, but still
there was strife. His advanced age
demanded peace, so after a year
he resigned and went back to
Louisville. But again public sentiment
decided matters, and again he returned
to Cincinnati in 1852 to be
welcomed with a mass meeting. His
triumph was short-lived, for
he contracted pneumonia after only a
few weeks and died after a
brief illness. While he was actually
engaged in clinical teaching
through most of his career, he was
nevertheless an able physiologist.
Had he not dissipated so much energy in
the feuds among various
schools in Cincinnati, he might have
gone into history as such.
After Shotwell's passing, Leonidas M.
Lawson (1812-1864) taught
physiology at the Medical College of
Ohio for several years, although
he was officially professor of materia
medica and pathology. Next
Samuel G. Armor (1819-1885) was
professor of physiology and
pathology, to be followed by John H.
Tate in 1856 as professor of
physiology, hygiene, and medical
jurisprudence. His tenure lasted
only two years. In the new Cincinnati
College of Medicine and
Surgery, Cornelius George Comegys
(1816-1896), who had just
returned from study with Charcot in
Paris, was made professor of
anatomy. A few months later he went
over to the newly established
Miami Medical College as professor of
the institutes (1852). With
its merger in 1857 into the Medical
College of Ohio, he con-
tinued to teach physiology, but
resigned a year later in one of the
perennial upheavals. In 1864 he was
reinstated, but resigned because
of ill health after four years.
In 1861 Comegys was followed by James
T. Hibberd (1816-
1903) as professor of physiology. When
he left after a year, W. W.
358
Ohio State Archaeological and Historical Quarterly
Dawson (1828-1895), who served until
Comegys was reinstated,
stepped into the vacancy. After the
latter's resignation, Edward
Rives (1833-1883) was professor of
physiology for a year, during
which he introduced for the first time
in America the use of a pro-
jection lantern as a means of
illustrating lectures. It was then called
the "Magic Lantern."
James F. Whittaker (1843-1900) was
professor of physiology
until 1879. In rather rapid succession
came Frederick Forchheimer
(1853-1913), who occupied the chair to
1895; B. Knox Rachford
to 1898; Allyn C. Poole to 1901;
William Muehlberg to 1908; and
E. M. Baehr, who was in charge in 1910
when the merger occurred
from which the college of medicine of
the University of Cincinnati
resulted. He was carried over after
Martin Fischer took charge.
In 1851 A. H. Baker, having failed to
secure an appointment on
the faculty of the Medical College of
Ohio, organized the Cin-
cinnati College of Medicine and Surgery
which was the first in the
general area to admit women. A separate
medical school for women
was in operation for a time under the
same management. Still
further, a dental department was in
operation for many years.
Here R. A. Spencer was the first
professor of physiology and
anatomy, but delegated physiology to
Robert Curran. In 1853 he
was followed by Charles Woodward;
Chandler B. Chapman, Robert
R. McIlvaine, J. H. Buckner, F. B.
Anderson, and J. Trush brought
the sequence up to 1872. R. B. Davey
served until 1877, when he
was replaced by Asa Brainard Isham
until 1880. He was the first
experimental physiologist in the entire
group in Cincinnati. His
studies with his father-in-law, Alonzo
Thrasher Keyt, on peripheral
circulation finally evolved into a
polygraph recognized by Marey as
superior to his own. Isham first
characterized the presphygmic
period, and recorded many other
original observations useful to
the modern cardiologist. These were
summarized and correlated
in a classical monograph in 1887.
William Judkin, J. H. Hazard,
and John M. Shaller apparently filled
out the period to 1902 when
the school closed.
The Miami Medical College reopened as a
separate institution
in 1865. Comegys' connection with this
institution has already been
noted. After the reorganization William
H. Taylor was professor
The Teaching of Physiology in
Ohio 359
of physiology, pathology, and morbid
anatomy(!) until 1872. Then
came J. C. McKenzie until 1880, and
Joseph Eichberg (1859-1908)
until 1894. O. P. Holt and Frank H.
Lamb completed the story to
the merger of 1910 which created a
great modern school from the
fragments of those gone before.
Martin H. Fischer (1879- ) graduated from Rush Medical
College in 1901. He had previously been
assistant in pathology and
physiology for a year each. For the year
following graduation he
was an associate in the latter. He then
went with Jacques Loeb to
California as assistant professor of
physiology but remained only
three years. For the next five years he
was professor of pathology
in Oakland College of Medicine and
Surgery.
In 1910 he was called to Cincinnati to
head the department of
physiology and has continued active to
retirement in 1950. He is
widely recognized as an able
investigator and lecturer. His most
important contributions have related to
the physical chemistry of
protein and water exchange. E. M. Baehr
continued to serve under
Fischer until his death in 1933. He
practiced medicine part time,
but did only sporadic research. His
most important activity was in
making the local medical profession
aware of progress in physiology.
Gustav Eckstein (1890- ) graduated from the Cincinnati
College of Dental Surgery in 1911 and
in 1922 became instructor
in physiology under Fischer. Two years
later he completed the
medical course but continued in the
department. In 1933 he was
promoted to assistant professor and
three years later to associate
professor. His investigations have all
been confined to neuro-
physiology.
Robert A. Kehoe (1893- ) graduated from the college of
medicine of the University of
Cincinnati in 1920 and was appointed
assistant professor of physiology. His
rank was raised to associate
professor in 1931, and to research
professor in 1939. When C. F.
Kettering endowed the laboratory of
applied physiology for the
study of industrial problems, he was
appointed director. His research
in that capacity has dealt with fatigue
and with problems of metal
poisoning.
While the chair of physiology in this
school is named in honor
of Joseph Eichberg, he never actually
made much contribution to
360
Ohio State Archaeological and Historical Quarterly
physiological knowledge. The modern
period was initiated by
Fischer. Able men have served at
various times, but their abilities
were expressed in other directions,
except Isham. Practically none
of Fischer's predecessors were trained
physiologists, although a few
had studied abroad with such men as
Claude Bernard.
Turning now to the opposite corner of
the state, we find up in
the Western Reserve a strong spirit of
rivalry engendered by the
establishment of the Medical College of
Ohio. This spirit took con-
crete form in 1834 when Willoughby
University was founded in the
village of Chagrin. Many of the
settlers had come from New York,
where the country medical college in
Fairfield was then at the acme
of prestige. Its most active president
was Dr. Westel Willoughby
just then at the peak of popularity.
Since the new school was modeled
after that at Fairfield, the name of
the village was changed to
Willoughby.
Apparently there was a great deal of
negotiation behind the
scenes which may be disregarded for
present purposes. Willoughby
University as such never materialized,
and the medical department
functioned alone. The seven faculty
members were all local prac-
titioners, and there is doubt that some
of them even claimed medical
degrees. George Jones was the first
professor of anatomy and phy-
siology, and T. W. Donovan was
professor of the institutes of
medicine. Jones was replaced after the
first year by Horace A. Ackley,
who in 1843 went to Cleveland as
professor of anatomy, phy-
siology, and surgery in the new medical
department of Western
Reserve College. Robert W. Paddock was
professor of anatomy and
physiology, dean, and secretary. He
functioned until the school was
moved to Columbus.
Returning to Western Reserve, John J.
Delamater (1815-1886),
an alumnus of New York University
School of Medicine (1844),
succeeded Ackley that same year and
served until 1856, when he
transferred to materia medica. Procter
Thayer (1823-1890) gradu-
ated from the medical school of Western
Reserve in 1849 and was
appointed demonstrator in anatomy.
Later he succeeded Delamater.
In 1863 he transferred to surgery, in
which field he attained to great
prominence. David Scott served for one
year as professor of phy-
siology and diseases of children (!!).
Isaac Newton Himes (1834-
The Teaching of Physiology in
Ohio 361
1895) served during the year of
1864-65, being followed by John
C. Ferguson (1828-1869) and John
Bennitt (1830-1869), each
remaining only a year, and by Joseph
Thatcher Woods (1828-1911),
who served two years. In the meantime
Himes had gone to Europe
to study microscopy. Upon returning, he
was appointed professor
of physiology and histology. This
change is significant of the grow-
ing dominance of physiology and of the
evolution of microscopic
science. This title was modified
further in 1872 to professor of
physiology and physiological and
microscopic anatomy. In 1881
Himes abandoned physiology entirely and
thereafter devoted all of
his attention to bacteriology and
pathology.
Charles Barnsdell Parker (1852-1918)
was graduated from the
medical department of Wooster
University in 1877 and was ap-
pointed demonstrator in anatomy, and
two years later, lecturer in
physiology. When Himes left physiology
in Western Reserve,
Parker replaced him with the title of
professor of physiology. After
five years he acquired gynecology also,
apparently at his own request,
for in 1890 he transferred to that
field entirely.
In 1863 G. C. E. Weber (1829-1912) was
dismissed from the
faculty of Western Reserve, and, as in
so many other similar in-
stances, retaliated by organizing a new
medical school in which
he was professor of physiology,
histology, and pathology. This
was first known as Charity Hospital
Medical College, but in 1870
it went under the nominal protection of
Wooster University. In
1868 he was succeeded by James H.
Salisbury, and the latter in
turn by Colin Mackenzie, then Daniel
Buttrick Smith, Louis B.
Tuckerman, and Arnold Peskind, up to
1891 when the most illus-
trious figure of this group appeared on
the scene.
George Washington Crile (1864-1943)
graduated from this school
in 1887 and soon began to lecture on
histology and minor surgery.
He became professor of histology and
physiology (note the
sequence) to serve until 1900, when he
transferred to Western
Reserve as professor of surgery.
In the meantime Wooster University
(1896) cast the school
adrift, and Ohio Wesleyan University
adopted it. In 1910 it merged
with Reserve. After Crile left, G. H.
Fitzgerald, an alumnus of
1898, gave cursory attention to
physiology for a few years, then
362
Ohio State Archaeological and Historical Quarterly
was followed by B. F. Hambleton for the
last five years. The latter
subsequently went to Vanderbilt, then
to Baylor.
After Parker left physiology in Reserve
in 1890, he was followed
by John Pascal Sawyer, who divided his
time for three years be-
tween physiology and clinical medicine.
He had studied in Germany
for a time, and when he decided to give
up physiology entirely,
recommended as his successor a man whom
he met there, Johannes
Wilhelm Gad (1842-1926), director of
the physiological institute
in the University of Berlin. He was
then the first full-time pro-
fessional physiologist, and the first
and only full-time member of
the faculty. This was too abrupt a
change to be well assimilated.
Difficulties arose at once over
compensation. Also, he was unable to
speak English clearly when lecturing.
This combination brought
about his resignation after one year,
and he returned to Europe
to become professor of physiology in the
University of Budapest
until 1911.
Christian Sihler (1848-1919) graduated
from the medical school
of the University of Michigan in 1871
and some years later went
to Johns Hopkins where he acquired a
doctorate in 1881. In 1888
he began to teach histology at Western
Reserve. In 1894 he re-
signed to become associate professor of
physiology in Wooster
University, and when Gad resigned, he
was appointed to that chair
also. Thus he served both institutions
for a time.
It had become apparent by this time
that the department of
physiology required some drastic
treatment in order to keep it
in line with the trends of development
in that discipline. A careful
survey of possible candidates was made.
Not many were available
in America. Newell Martin's men were
all placed. Bowditch at
Harvard had made no special effort to
train physiologists. Lombard
had not yet gotten under way at
Michigan, and Reichert at Penn-
sylvania had not yet trained anyone.
Consequently, there was noth-
ing to do but look abroad. George Neil
Stewart (1860-1930) had
been trained in Edinburgh and had
followed up with advanced
study in Berlin, Strasbourg, and
Cambridge. He had taught in a
number of minor positions in Edinburgh,
Victoria, Aberdeen, and
Cambridge. At that time he was with
Bowditch as a research asso-
ciate. He was professor of physiology
and histology at Western
The Teaching of Physiology in
Ohio 363
Reserve until 1903, when he went to the
University of Chicago,
where he remained four years. In 1907
he was called back to Re-
serve as director of the H. K. Cushing
Laboratory of Experimental
Medicine. He was the first of the
modern school of physiologists to
exert any appreciable influence on this
school. His textbook of
physiology was widely used for many
years. One of the outstanding
products of Stewart's first tenure at
Reserve was Torald Sollmann,
who served as demonstrator in
physiology and histology (1896-98),
then went over to pharmacology.
Stewart's successor at Reserve was J.
J. R. Macleod (1876-1935).
He had been trained in Aberdeen,
Leipzig, and Cambridge, and
was demonstrator in physiology in
London, then in biochemistry,
and at the time of his call to Reserve,
was Mackinnon Research
Scholar in the Royal Society. He
remained as professor of physiology
until 1918 when he was called to
Toronto.
Carl John Wiggers (1883- ) received the medical degree
from Michigan in 1906 and continued in
the department teaching
and investigating. Five years later he
went to Cornell, where he
remained until 1918 when he was called
to Reserve. He developed
a strong department and has turned out
many students who now
hold positions as physiologists, one of
them being his son, Harold
C. Wiggers, now professor of physiology
in Albany Medical Col-
lege. Carl Wiggers' influence on
American physiology has been quiet
and progressive.
After the Willoughby Medical College
moved to Columbus in
1846, the name was changed to Starling
Medical College in recog-
nition of the patronage of Lyne
Starling in supplying funds for
the first hospital. It will be recalled
that Robert H. Paddock served
two years as professor of physiology,
then was succeeded by Francis
Carter under the title of professor of
physiology and general
pathology. In 1852 Paddock was recalled
for two years more, this
time as professor of anatomy and
physiology. Then came John
Dawson, S. D. Turney, and H. C. Pearce,
carrying the story up to
1875. Then W. J. Conklin (1844-1916)
was professor of phy-
siology and physiological anatomy to
1879. He later went into
pediatrics. David Todd Gilliam served
to 1884, then concentrated
on gynecology.
364
Ohio State Archaeological and Historical Quarterly
As in other centers, factionalism and
personal jealousies in 1875
culminated in a schism from which
emerged the Columbus Medical
College, which operated until 1892. At
that time it closed and part
of the faculty returned to Starling.
For the first four years, J. F.
Baldwin was professor of physiology. He
later became one of the
capital city's most prominent surgeons.
He was followed by William
Warner (1879-83), Howard Jones
(1883-86), George M. Waters
(1886-91), and G. F. Jewett (1891-92).
The other portion of the faculty, not
being satisfied to rejoin
the Starling faculty, assembled
additional associates, and organized
the Ohio Medical University. This title
was justified by the inclu-
sion of departments of dentistry and
pharmacy. Clovis M. Taylor
was professor of physiology until 1899.
Apparently instruction was
still done by lectures and crude
demonstrations, as no student teach-
ing laboratory was established for
nearly twenty years more. How-
ever, the microscope was coming into
more general use.
And now we come to a figure who has
received less recognition
for an important service to American
physiology than any other
worker in the past century. This man
was Albert M. Bleile (1856-
1933), who graduated in 1876 from
Starling Medical College. The
next three years were spent in Paris,
Vienna, and Leipzig, although
it is not clear just what were his
objectives in going abroad. There
is no good evidence that he then
intended to become a physiologist.
But he came into association with Carl
Ludwig, and thereafter
never lost touch with this great
master.
When Bleile returned to America, he
began to practice medicine.
When Gilliam resigned in 1884, Bleile
succeeded him as professor
of physiology and pathology in
Starling. Except for the year on
leave of absence (1897-98), he served
that post continuously until
1899. He then transferred to Ohio
Medical University, and one of
his students, Charles B. Morrey, later
professor of bacteriology,
succeeded to the chair, which he served
until 1907, when Starling-
Ohio Medical College was created by the
merger of the two schools.
A still more significant development
had taken place in the mean-
time. In 1891 it was decided that an
academic course in physiology
should be developed at Ohio State
University. Bleile was already
on the ground still only a decade away
from his work with Ludwig.
The Teaching of Physiology in
Ohio 365
He was asked to organize the work while
still continuing his work
in Starling Medical College. Apparently
he had never been greatly
attracted to medical practice, so he
gave that up completely and
devoted all of his time to an academic
career. He not only established
a department of physiology, but
included instruction in bacteriology,
microscopy, and physiological
chemistry. Each of these subdivisions
eventually expanded into autonomous
departments of instruction.
Bleile popularized college physiology
to a degree that hundreds of
students were electing the courses in a
few years. In addition he
taught courses in physiology and
physiological chemistry for students
in the college of veterinary medicine.
It has been stated that the reason he
abandoned research after
his earlier years was because he had
become disgusted with the
superficiality of so much that passed
for scientific investigation.
However, this essayist is of the opinion
that the real reason was that
he became absorbed in an investigation
so profound and elusive
that he was never able to bring it to a
successful culmination and
would not publish progress reports
because they might be mis-
leading.
This conclusion resulted from
observations made while teaching
a college course in close association
with him in the school year of
1916-17. This author occupied an office
with a door communicating
with his private laboratory, and saw
him spend many hours work-
ing over apparatus very intensively. He
never confided in anyone,
but gave the impression that he was
trying to apply physico-
chemical methods to the study of
protoplasm. At any rate, he was
either engaged with a great problem or
he was simply puttering.
His very character precludes the
possibility that he could do the
latter.
He was a real pioneer in that he
developed on a large scale
coeducational instruction in physiology
at a university level. In
this sense he deserves credit beyond
any accorded to him up to this
time. He was stern and forbidding in
mien, so that one did not
feel free to open discussion with him.
Yet he was kindly and con-
siderate when he could help a younger
worker. When Clyde Brooks
became head of the department in 1916,
Bleile laid aside his own
private interest and entered into a
cooperative research project
366 Ohio
State Archaeological and Historical Quarterly
with Brooks on an analysis of the
physical forces involved in blood
pressure.
When Starling and the Ohio Medical
College were merged in
1907, W. J. Means became dean.
He recognized that his own training
had not been adequate, and resolved to
exert every influence to
bring the school to a higher level. His
frequent inspection trips
actually served as sources of
information, and he never returned
from one of them without disgorging
volumes of observations about
the internal workings of other schools.
Everything that could be
adapted to his needs, he used without
apology or embarrassment.
Bleile and his assistants, R. J.
Seymour and E. P. Durant, Sr., were
too well situated in the university
department to desire to give full
time to the medical and dental courses.
It seemed imperative, there-
fore, that provision be made for
strengthening the course in phy-
siology.
In 1910 Roy G. Hoskins (1880- ) received a doctorate in
physiology under Cannon at Harvard. In
fact he was the first so
honored. He undertook the establishment
of a modern teaching
laboratory based on the Harvard plan.
The actual installation of
the new equipment did not take place
until 1911. In the first year
Clayton M. McPeek, then a recent
medical graduate, was assisting
in both histology and physiology. J.
Clifton Edwards also was a
laboratory assistant.
In the second year this author was
first employed as animal
caretaker, dividing time between
physiology and bacteriology.
Hoskins, seeing the necessity for
additional help, persuaded the
dean to readjust the time allotment to
include storeroom keeper
and laboratory assistant. Not having
had the course, being just
then admitted to the sophomore class,
Hoskins himself undertook
to tutor me in advance. Much of
Hoskins' early efforts aroused
antagonism on the part of conservative
elements, but Dean W. J.
Means, F. L. Landacre, Ernest Scott,
Carl Spohr, Verne Dodd, Jack
Means, Hal Wright, and C. W. McClure
gave him loyal support.
Many members of the group engaged in
research with him. His
classical studies on the adrenal had
just been initiated and were
pursued actively during the three years
of his tenure.
The Teaching of Physiology in
Ohio 367
In 1913 Hoskins was called to
Northwestern, Edwards went for
a year to Lincoln Memorial Medical
College, and McPeek became
acting head of the department. Edwards
returned after a year on a
part-time basis. When the Starling-Ohio
Medical College was taken
over by Ohio State University in 1914,
no immediate change was
made in the status of the two groups.
McPeek and Reed, with two
assistants, conducted the work for
medical and dental students.
Bleile, Seymour, Durant, and R. L.
Mundhenk made up the staff
for the college courses.
In 1916 Clyde Brooks (1881- ) was called from the University
of Pittsburgh as professor of
physiology, pharmacology, and bio-
chemistry. The last course had been
taught by several different
persons, among them John F. Lyman and
Frederick M. Stanton. The
first course in pharmacology had been
instituted in 1911 under
the guidance of Harry Burbacher, dean
of the pharmacy depart-
ment. This department was discontinued
because the university
already had a well organized college of
pharmacy. Burbacher sub-
sequently went into medicine, so that
it was fortuitous that Brooks
had already had considerable experience
in teaching pharmacology
in Washington University, the
University of Chicago, and in Pitts-
burgh. Also he established the policy
of exchange of personnel
between the two divisions of the
combined department. Later, both
biochemistry and pharmacology were made
autonomous departments.
Bleile accepted without question his
supersession and even displayed
considerable enthusiasm toward the new
regime.
In 1920 Brooks was called to Alabama,
and a year later Hoskins
was called back to Ohio State and
remained until 1927 when he was
made director of the neuro-endocrine
foundation, from which posi-
tion he retired in 1947.
Among those trained under Hoskins
during the second period
of tenure were Milton O. Lee, E. C.
Albritton, and Fred Hitchcock.
Leonard B. Nice (1882- ) was called to the department from
the University of Oklahoma after
Hoskins left in 1927 and remained
until 1936. Seymour was department
administrator from 1927 to
1934 when Frank A. Hartman was called
from the University of
Buffalo and functioned as head of the
department until 1947 when
368
Ohio State Archaeological and Historical Quarterly
he was made research professor. Eric
Ogden (1903- ) came
from the University of Texas in 1949 to
become head of the de-
partment.
There have been other schools in which
physiology has had only
insignificant development. Homeopathic
schools in general have
given little attention to physiology.
The University of Toledo
operated a medical college for a number
of years, but physiology
was in the hands of local practitioners
throughout its history, and
cannot be said ever to have attained to
a modern status.
Charles G. Rogers of Oberlin College
has developed a high
grade program in general physiology,
but for the most part, physi-
ology in Ohio as elsewhere has reached
its most advanced evolution
in the medical colleges. Also as
elsewhere there has been constant
conflict between the influences
demanding more attention to applied
aspects of physiology, and those
attempting to maintain physiology
as a scientific discipline. What the
outcome of this tug-of-war
will be, only time can determine.
Meantime the problem is pro-
voking study and discussion from which
the next stage of evolution
will emerge in due time.
The history of research in Ohio is certainly
on a par with that
elsewhere, being characterized by
steady, prosaic advance rather
than by sporadic outbursts and
recessions. And as everywhere else,
knowledge of physiology has been and is
being contributed from
many sources. Immunology, embryology,
physiological chemistry,
pharmacology, nutrition, veterinary
medicine, clinical surgery, in-
ternal medicine, hematology, the
specialties, biology, zoology, or-
ganic and physical chemistry,
enzymology, and radiobiology are
making contributions to fundamental
physiological knowledge quite
as important as those made by the
physiologists. Current conditions
will reduce the training of specialists
in physiology. Are we turning
back to the conditions of a century ago
when one man might teach
physiology along with one to four
additional subjects? It will be
worth while giving attention to that
problem in the immediate
future.
DEVELOPMENT OF THE TEACHING OF
PHYSIOLOGY
IN OHIO*
by C. I. REED
Professor of Physiology, University
of Illinois, Chicago Professional Colleges
In order to bring the subject into
perspective it is necessary to
go back to the year 1726, when the
first curricular representation of
physiology was accorded by the
University of Edinburgh in appoint-
ing Andrew Sinclair professor of the
institutes of medicine. As
applied later, this title very often
covered much more than the con-
ventional scope of physiology as a
study of function in the healthy
organism. Not infrequently a professor
of the institutes and a pro-
fessor of physiology served
simultaneously in the same institution.
The first recognition came in America,
not in the first medical
school, but in the second one, that
founded in King's College, now
Columbia University, in 1769 when Peter
Middleton was appointed
professor of physiology and pathology.
Of course, the physiology
of that day was something quite
different from what is so desig-
nated today. Nevertheless, this
gentleman was a highly trained,
capable physician. The title lapsed
with his death in 1780, but was
restored in 1806 when a radical
reorganization took place which
gave Benjamin De Witt the chair of the
institutes.
Caspar Wistar was made professor of the
institutes in the Uni-
versity of Pennsylvania in 1789, and in
1792 a reorganization placed
Benjamin Rush in that chair. In point
of chronology this is the
oldest continuously functioning
department of physiology in North
America, as there is direct continuity
through several generations to
the present department in that
university. There was a brief flurry
of original research in the first few
years of the nineteenth century,
but this was not sustained. In the
medical school founded in Harvard
College in 1782 no provision was made
for teaching physiology
for nearly sixty years when Oliver
Wendell Holmes became pro-
fessor of anatomy and physiology.
* This article was read before the
Committee on Medical History and Archives of
the Ohio State Archaeological and
Historical Society at its annual meeting, held at
the Ohio State Museum on April 28, 1951.
355